DNA甲基化转移酶,DNA methyltransferase
1)DNA methyltransferaseDNA甲基化转移酶
1.Objective:To study transcription level and catalytic activity ofDNA methyltransferase (Dnmts) in lung cancer cell line A549 exposed in 5-Aza-CdR (5-Aza-2’-deoxycitydine),and the role of Dnmts in the process.目的:研究5-氮杂-2’-脱氧胞苷(5-Aza-2’-deoxycitydine,5-Aza-CdR)处理肺癌细胞株A549后,DNA甲基化转移酶(DNA methyltransferase,Dnmts)转录水平及其活性的变化,以及细胞生长状态的改变。
英文短句/例句
1.The Relationship between the Expression of DNA Methyltransferase and Multidrug Resistance Gene ABCG2 in Breast Cancer乳腺癌组织中DNA甲基化转移酶与多药耐药基因ABCG2表达的关系
2.Role of DNA Methyltransferase 1 in DNA Methylation of Pancreatic Cancer;DNA甲基转移酶1在胰腺癌DNA甲基化中作用机制的研究
3.DNA methyltransferases:classification,functions and research progressDNA甲基转移酶分类、功能及其研究进展
4.Progress in DNA methyltransferase inhibitorsDNA甲基转移酶抑制剂的研究进展
5.Expression of DNMT1 mRNA in uterine cervical carcinoma tissue宫颈癌组织中DNA甲基转移酶1mRNA的表达
6.Expression of DNA methyltransferase 1(DNMT1)in lung adenocarcinoma and its prognostic significance肺腺癌中DNA甲基转移酶1的表达
7.Isolation and Expression Analysis of DNA Methyltransferase Genes in Strawberry and Apple草莓和苹果DNA甲基转移酶基因分离及表达分析
8.DNA methyltransferases:the role in regulation of gene expression and biological processesDNA甲基转移酶的表达调控及主要生物学功能
9.Effects of DNA methyltransferase activity in lung cancer cells treated with 5-Aza-CdR5-Aza-CdR对肺癌A549细胞DNA甲基转移酶活性的影响
10.The Expression of DNMT1、HDAC1 and PR in Endometriosis;DNA甲基转移酶1、组蛋白去乙酰化酶1和孕激素受体在子宫内膜异位症中的表达
11.Expression and clinical significance of MGMT in patients with esophageal carcinomaO~6-甲基鸟嘌呤-DNA甲基转移酶在食管癌患者的表达及临床意义
12.Expression of DNA Methytransferase 1 Protein in Transitional Cell Carinoma of the Bladder and Its Clinical SignificanceDNA甲基转移酶1蛋白在膀胱移行细胞癌中的表达及其临床意义
13.Effect of Volatile Chemicals in the Air of Newly Decorated Rooms on O~6-methylguanine-DNA Methyltransferase Expression in Lung,Liver,Kidney and Testicle Tissues of Mice居室空气中主要挥发性化学物对小鼠脏器O~6-DNA甲基转移酶表达的影响
14.The Clinical Value of the Expression of DNA Methyltransferases Genes in Acute Leukemia Patients;急性白血病患者DNA甲基转移酶基因的表达及其临床意义
15.Effects of interference of DNA methyltransferases in re-expression of cancer/testis antigens in hepatocellular carcinoma cellsDNA甲基转移酶基因干扰对HepG2细胞癌-睾丸抗原再表达的影响
16.Clinical Prognostic Value of Expression of DNA Methyltransferases Genes in Children with Acute Leukemia急性白血病患儿DNA甲基转移酶基因表达的临床预后价值
17.Study on Expression of DNMT1 in Transitional Cell Carcinoma of Bladder by Real-time PCR and Its Clinical Significance;膀胱癌中DNA甲基转移酶1表达的实时定量检测及临床意义
18.RNA Interference-Mediated Knockdown of DNA Methyltransferase (DNMT1) in Human Lung Cancer Cell;应用RNA干涉抑制肺癌细胞高表达的DNA甲基转移酶1（DNMT1）的研究
相关短句/例句
de novo DNA MethyltransferaseDNA从头甲基化转移酶
1.Objective To investigate the mRNA expression ofde novo DNA Methyltransferase(DNMT1/3a/3b) and methyl-CpG Binding Protein2(MeCP2) in spermatozoon by qRealTime-PCR.目的通过体外分离成熟的精子,利用实时荧光定量PCR(qRealTime-PCR)检测其是否表达DNA从头甲基化转移酶(DNMT1/3a/3b)及甲基CpG结合蛋白(MeCP2),为精子中甲基化表观修饰研究提供依据。
3)DNA methyltransferases 3ADNA甲基转移酶3A
1.Objective To investigate the function ofDNA methyltransferases 3A(DNMT3A)in a series of biological process and carcinogenesis and to construct an eukaryotic siRNA targeting on DNMT3A to suppress the expression of DNMT3A gene.目的:构建DNA甲基转移酶3A(DNA methyltransferases 3A,DNMT3A)siRNA重组质粒稳定表达载体,为进一步探讨DNMT3A在多种生物学过程及肿瘤发生发展中的机制提供工具。
4)DNA methyltransferaseDNA甲基转移酶
1.Effects of preimplantation embryos on expressions ofDNA methyltransferase 1 in mouse oviduct epithelial cells;小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶1表达的影响(英文)
2.Effects of mouse preimplantation embryo on expression ofDNA methyltransferase-1 mRNA in mouse oviductal epithelium.;小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶-1 mRNA的降调节作用
3.Expression of mRNA forDNA methyltransferase 1, 3a and 3b in bladder carcinoma;膀胱癌DNA甲基转移酶1、3a、3b基因的表达
5)DNA methyltransferase 1DNA甲基转移酶1
1.Expression ofDNA methyltransferase 1 in human gastric cancer tissue and its significance;DNA甲基转移酶1在胃癌组织中的表达及意义
2.Expression ofDNA methyltransferase 1 in human cervical carcinoma tissue and cells and its significance;DNA甲基转移酶1在子宫颈癌组织和细胞中的表达及意义
3.Expression ofDNA methyltransferase 1 in transitional cell carcinoma of bladderDNA甲基转移酶1蛋白在膀胱移行细胞癌中的表达及其临床意义
6)DNA methyltransferasesDNA甲基转移酶
1.DNA methylation catalyzed byDNA methyltransferases interacts with histone modification to inhibit gene transcription,induce gene silencing at the participation of many regulators.DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。
2.It may result from down-regulatingDNA methyltransferases, DNMT1 and DNMT3B, or up-regulating the histone acetylation that allows chromatin unfolding and the accessibility of regulators for transcriptional activation in the p15 promoter.应用甲基化特异性聚合酶链反应(MSP)检测PHI作用前后Molt-4细胞株p15基因甲基化状态的变化;半定量逆转录-聚合酶链反应(RT-PCR)检测Molt-4细胞经过PHI处理后DNA甲基转移酶DNMT1、DNMT3A、DNMT3B、p15基因的mRNA的表达变化;用蛋白免疫印迹(Western blotting)检测Molt-4细胞经过PHI处理后的P15蛋白的表达。
3.Objective To investigate the relationship between the expression ofDNA methyltransferases(DNMT)and clinical prognosis in children with acute leukemia(AL).目的通过检测DNA甲基转移酶(DNMT)基因在AL患儿中的表达水平,探讨其与临床预后之间的相关性。
延伸阅读
酒化酶、醇酶、发酵酶分子式：CAS号：性质：又称酒化酶、醇酶、发酵酶。从酵母中分离而得的一系列酶。不耐热。它能催化酒精发酵反应，与糖酵解有关，如磷酸化酶、醛缩酶、葡萄糖磷酸变位酶、葡萄糖6-磷酸酶等。
