问题补充：
He made one big mistake, and , , lost his job.
A. in a word
B. in fact
C. at last
D. as a result
答案：
A. in a word
B. in fact
C. at last
(答案→)D. as a result
解析：词义辨析题。A. in a word 总之B. in fact 事实上C. at last 最后 D. as a result结果句意：他犯了一个大错误结果丢了工作。根据语境选D
